I-Doxycycline Hyclate(24390-14-5)
Ingcaciso yeMveliso
● I-Doxycycline Hcl yi-antibacterial spectrum isondele kakhulu kwi-Tetracycline kunye ne-Terramycin, kodwa inesiphumo esingcono, yiba novelwano kwi-Staphylococcus Aureus ye-tetracycline-resistant, i-oxytetracycline, ixesha elide. usulelo lwemiphunga, tonsillitis etsolo, mycoplasma inyumoniya, usulelo lwe-urinary tract, ityhefu yegazi, i-bacillary dysentery, i-lymphadenitis ebukhali, njl. Idume kakhulu kwisigulane se-Nephropathy ngenxa yetyhefu engabonakaliyo kwizintso.
● I-Doxycycline Hyclate luhlobo lwetyuwa lwe-hyclate lwe-doxycycline, i-synthetic, i-broad-spectrum ye-tetracycline i-antibiotic ebonisa umsebenzi we-antimicrobial.I-Doxycycline hyclate ibophelela ngokubuyela umva kwi-30S ribosomal subunit, mhlawumbi kwi-50S ribosomal subunit ngokunjalo, ngaloo ndlela ivalela ukubophelela kwe-aminoacyl-tRNA kwi-mRNA-ribosome complex.Oku kukhokelela ekuthinteleni ukwakheka kweeprotheyini.Ukongezelela, le arhente ibonise ukuvinjelwa komsebenzi we-collagenase.
Isicelo
I-Doxycycline Hyclate isetyenziselwa ukunyanga iintlobo ezininzi zezifo zebhaktheriya, kubandakanywa nezo zibangela i-acne.I-Doxycycline Hyclate ikwasetyenziselwa ukuthintela isifo seengcongconi.I-Doxycycline Hyclate yaziwa njenge-antibiotic ye-tetracycline.Isebenza ngokunqanda ukukhula kwebhaktheriya.Le ntsholongwane iphatha kuphela usulelo lwebhaktiriya.
| Izinto | Iinkcukacha | Iziphumo |
| Imbonakalo | Umgubo wekristale otyheli | Iyahambelana |
| Ukuchongwa | TLC | Iyahambelana |
| sulphuric acid reaction umbala omthubi kukhula | Iyahambelana | |
| inika ukusabela kweekloridi | Iyahambelana | |
| PH | 2.0~3.0 | 2.3 |
| Ukunyanyiswa okuthe ngqo | kwi-349nm e(1%) 300~355 | 320 |
| Ukujikeleza okuthe ngqo | -105 ~ -120 ° | -110 ° |
| Iintsimbi ezinzima: | ≤50ppm | < 20ppm |
| Ukungcola okufunxa ukukhanya | kwi-490nm ≤0.07 | 0.03 |
| Izinto ezinxulumeneyo | I-6-epidoxycycline ≤2.0%metacycline ≤2.0% I-4-epidoxycycline ≤0.5% (ep5) I-4-epi-6-epidoxycycline ≤0.5% (ep5) i-oxytetracycline ≤0.5% (ep5) Nakuphi na okunye ukungcola ≤0.5% ukungcola okungachongwanga ≤0.1% (ep5) | 1.6%0.1% Ayifunyanwa Ayifunyanwa Ayifunyanwa Ayifunyanwa Ayifunyanwa |
| I-Ethanol | 4.3~6.0% (m/m) | 4.5% |
| Uthuthu olune-sulphated | ≤0.4% | 0.05% |
| Amanzi | 1.4~2.8% | 1.8% |
| Isivavanyi | 95.0 ~ 102.0% ( c22h25cln2o8) ngokusekelwe kwi-anhydrous, into engena-ethanol | 98.6% |
| Ukuqukumbela | Ngokuhambelana ne-USP32 | |
