Ukusebenza kunye nemiphumo ye-Magnolia bark Extract

 

I-Magnolia bark extract ikhutshwe kwigxolo leengcambu zeyeza zendabuko zaseTshayina i-Mangnolia officinalis, kunye nezithako zayo ezisebenzayo yi-Huperzol, kunye ne-Honokiol, i-Magnolol ibonise ukuba zombini i-Magnolol ehlanjululwe kakhulu kunye ne-Magnolol ibonisa imisebenzi enamandla ye-pharmacological, ngakumbi kwi-antibacterial, anti-inflammatory, ukuchasana nokukhathazeka, ukuphuculwa kokulala, i-anti-tumor, i-antioxidant kunye neminye imiba yokusebenza kwempumelelo ebalulekileyo.

Izithako ezisebenzayo: Honokiol, Magnolol.Umthombo we-Botanical: iyeza laseTshayina i-Magnolia officinalis Rehder et Wilson elukhumbeni lwempembelelo ye-antimicrobial yezithako ezisebenzayo.Le mveliso i-off-white powder crystals.Inyibilika kwibenzene, ether, chloroform, acetone, insolble in water, diluble in dilute alkali solution, fumana ityuwa yesodium.Iqela le-phenolic hydroxyl lifakwa kwi-oxidized ngokulula, ngelixa iqela le-alyl lilula ukwenza ukusabela okongeziweyo.Inefuthe elikhethekileyo nelihlala ixesha elide lokuphumla kwezihlunu kunye nefuthe elinamandla le-antibacterial, kwaye inokuthintela ukudityaniswa kweplatelet.Ngokweklinikhi, isetyenziswa kakhulu njengeyeza lokulwa ne-antibacterial kunye ne-antifungal.Le mveliso kufuneka ivalwe kwaye ikhuselwe ekukhanyeni, kwaye igcinwe kwindawo eyomileyo, epholileyo kunye neyomoya.

1,Ipropathi efanelekileyo ye-antibacterial

Uphononongo lubonise ukuba i-Magnolia bark extract ine-spectral antibacterial (inhibitory) effect, enefuthe elinamandla lokuthintela kwiibhaktheriya ze-Gram-positive kunye ne-Gram-negative, kunye neempawu ze-antibacterial zizinzile, akukho lula ukuba zonakaliswe ngubushushu, i-asidi kunye ne-alkali.Ngokomzekelo, i-Escherichia coli, i-Staphylococcus aureus, i-Candida albicans, i-Aspergillus brasiliensis.

2,I-anti-caries elungileyo kunye nokusebenza kwe-anti-moth-eten

Uphononongo lubonise ukuba i-Magnolia bark extract inefuthe elihle lokuthintela kwi-caries-ebangela ibhaktheriya ehambelana nomlomo womlomo, i-caries-ebangela ibhaktheriya yomlomo ikakhulu ibhekisela kwi-Streptococcus pyogenes, i-Streptococcus haematocritus, i-Actinobacillus viscosus, i-Actinobacillus nei, kunye ne-Lactobacillus lactis.Uphando lubonisa ukuba isicatshulwa seMagnolia bark extract sinempembelelo ecacileyo yokuthintela ukukhula kunye nemveliso ye-asidi yeebhaktheriya ezibangela i-caries, kunye nokuveliswa kwayo kwe-glucosyltransferase, i-amylase kunye ne-glucosidase.

3,Iimpawu ezichasayo

Uphononongo lubonise ukuba izithako ezisebenzayo ze-Magnolia bark extract zineempembelelo ezibalulekileyo zokuthintela kwizinto ezibalulekileyo ze-pro-inflammatory, ezifana nabalamli abavuthayo NO, i-interleukin 4 (IL-4), i-interleukin 10 (IL-10), kwaye ngoko bane-anti-anti- elungileyo. iimpawu ezivuthayo.

4,I-Antioxidant

Uphononongo lubonise ukuba isicatshulwa seMagnolia bark extract sinemiphumo emihle ye-antioxidant, enokuthintela i-lipid peroxidation kwaye icothise inkqubo yokuguga.Inokuthintela i-lipid peroxidation kwaye icothise inkqubo yokuguga ngokukhupha i-radicals yamahhala (DPPH, OH-), ukuphucula umsebenzi we-antioxidant enzymes, kunye nokuthintela indlela ye-lipid peroxidation.