Cimetidine(51481-61-9)
Ingcaciso yeMveliso
● I-Cimetidine ineziphumo ezikhuselayo kunye nezikhuselayo kwi-gastritis eyingozi ebangelwa ukucaphuka kweekhemikhali, kwaye iyasebenza kakhulu kuxinzelelo lwesilonda sesisu kunye nokopha kwesisu esiphezulu.
● I-Cimetidine yi-histamine H2 receptor impedant, esetyenziselwa kakhulu ukuthintela ukukhutshwa kwe-asidi yesisu, enokuthi inqanda ngokubonakalayo i-basal kunye ne-nocturnal gastric secretion, kwaye iphinde inqanda ukukhutshwa kwe-asidi ye-gastric ebangelwa yi-histamine, i-peptide ye-peptide gastrin, i-insulin kunye nokuvuselela ukutya, kwaye iyenze. i-acidic encinci.I-Cimetidine inefuthe elikhuselayo kunye nokukhusela kwi-gastritis eyingozi ebangelwa ukukhuthazwa kweekhemikhali, kwaye iyasebenza kakhulu kuxinzelelo lwesilonda sesisu kunye nokopha kwesisu.
●Umgangatho woMgangatho: USP
| Into | Umgangatho | Isiphumo |
| Ibonakala | Imhlophe okanye phantse ngelixa iCrystalline Powder engenavumba, incasa ekrakra | Confbnn |
| Ukuchongwa | ||
| A:(IR) | Ukuhambelana ne-USP Cimetidine RS | Vumelana |
| B:(UV) | Ukuhambelana ne-USP Cimetidine RS | Vumelana |
| Uvavanyo (kubalwa kwisiseko esomileyo) | 98.0-102.0% | 99.9% |
| Ukungcola | ||
| Intsalela ekutshisweni | NMT 0.2% | Vumelana |
| Iintsimbi ezinzima | NMT 20ppm | Vumelana |
| Ukungcola kwezinto eziphilayo | Nakuphi na ukungacoceki komntu NMT 0.2% | NMT 0.2% |
| Ubumdaka bubonke i-NMT 1.0% | NMT 1.0% | |
| Uluhlu lokunyibilika okanye iqondo lobushushu | 139-144 °C | 141-143 * C |
| Ilahleko ekomisweni | NMT 1.0% | 0.22% |
| Izinyibilikisi ezishiyekileyo (ethanol) | NMT 0.5% | NMT 0.5% |
